Hounded by terrible twisted greed (8)
I believe the answer is:
badgered
'hounded' is the definition.
(I've seen this in another clue)
'by terrible twisted greed' is the wordplay.
'by' means one lot of letters go next to another.
'terrible' becomes 'bad' (similar in meaning).
'twisted' indicates an anagram.
'greed' anagrammed gives 'gered'.
'bad' next to 'gered' is 'BADGERED'.
(Other definitions for badgered that I've seen before include "Harassed" , "Pestered" , "Annoyed persistently" , "hassled" , "chivvied" .)