House record label is after soprano initially (4)
I believe the answer is:
semi
'house' is the definition.
(short for semi-detached)
'record label is after soprano initially' is the wordplay.
'record label' becomes 'emi' (British record label).
'is after' is a charade indicator (letters next to each other).
'initially' suggests taking the first letters.
The first letter of 'soprano' is 's'.
'emi' put after 's' is 'SEMI'.
(Other definitions for semi that I've seen before include "House joined to another" , "Style of house" , "Residence" , "eg Half a house" , "Type of house (UK) - type of truck (US)" .)