How any pig can be made profitable! (6)
I believe the answer is:
paying
'profitable' is the definition.
(similar in meaning)
'how any pig' is the wordplay.
'how' indicates an anagram (I've seen this in other clues).
'any'+'pig'='anypig'
'anypig' is an anagram of 'PAYING'.
'can be made' acts as a link.
(Other definitions for paying that I've seen before include "Discharging a debt" , "Giving money for good or services" .)