Crossword Genius

How things tend to go in a tragedy (4)

Ross

I believe the answer is:

awry

(Other definitions for awry that I've seen before include "Amiss, askew" , "Crooked, twisted to one side" , "Crooked; amiss" , "turning to one side" , "Wrong, amiss" .)

I've seen this clue in the Universal.
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