Humble cleric taking me to heart (6)
I believe the answer is:
demean
'humble cleric' is the definition.
'demean' can be an answer for 'humble' (demeaning is a kind of humbling). I'm unsure of the 'cleric' bit.
'taking me to heart' is the wordplay.
'taking' indicates putting letters inside.
'to heart' becomes 'dean' (I am not sure about this - if you are sure you should believe this answer much more).
'me' going inside 'dean' is 'DEMEAN'.
Can you help me to learn more?
(Other definitions for demean that I've seen before include "make base" , "'Put down, degrade (6)'" , "Degrade, humiliate" , "Lower in reputation, shame" , "Humble" .)