Humble lady follows men taking drug, being a skinflint (10)
I believe the answer is:
cheapskate
'a skinflint' is the definition.
(cheapskate is a kind of skinflint)
'humble lady follows men taking drug' is the wordplay.
'humble lady' becomes 'Kate' (BBC wildlife presenter Kate Humble).
'follows' means one lot of letters go next to another.
'men' becomes 'chaps' (chap can mean a man).
'taking' means one lot of letters goes inside another.
'drug' becomes 'e' (E is another name for ecstasy).
'chaps' placed around 'e' is 'cheaps'.
'kate' after 'cheaps' is 'CHEAPSKATE'.
'being' acts as a link.
(Other definitions for cheapskate that I've seen before include "Tightwad" , "Mean type" , "ungenerous person" , "Miserly person" , "Scrooge" .)