I cannot work and carry (7)
I believe the answer is:
contain
'carry' is the definition.
('contain' can be a synonym of 'carry')
'i cannot work' is the wordplay.
'work' is an anagram indicator.
'i'+'cannot'='icannot'
'icannot' with letters rearranged gives 'CONTAIN'.
'and' acts as a link.
(Other definitions for contain that I've seen before include "I cannot (anag) - hold back" , "Keep within limits or have within" , "Hold within, suppress (7)" , "Include - restrict" , "Carry" .)