Crossword Genius

I gave Reg fluid for pain (8)

Ross

I believe the answer is:

aggrieve

'pain' is the definition.
(thesaurus)

'i gave reg fluid' is the wordplay.
'fluid' indicates an anagram.
'i'+'gave'+'reg'='igavereg'
'igavereg' anagrammed gives 'AGGRIEVE'.

'for' acts as a link.

(Other definitions for aggrieve that I've seen before include "Distress (someone)" , "Distress, afflict" , "Cause pain to; distress" , "Cause offence or injury to" , "Press heavily upon; distress" .)

I've seen this clue in The Independent.
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