I say, dispose of this one-room dwelling (4)
I believe the answer is:
cell
'room dwelling' is the definition.
'cell' can be an answer for 'room' (I've seen this before). I'm not sure about the 'dwelling' bit.
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for cell that I've seen before include "Place of confinement" , "American mobile" , "Small compartment" , "Unit of animal or plant structure" , "Animal or plant building unit" .)