I unusually retain resistance to change (7)
I believe the answer is:
inertia
'resistance to change' is the definition.
(I've seen this before)
'i unusually retain' is the wordplay.
'unusually' indicates anagramming the letters.
'retain' anagrammed gives 'nertia'.
'i'+'nertia'='INERTIA'
(Other definitions for inertia that I've seen before include "Lack of movement" , "Torpor" , "Passivity" , "Stagnating state" , "Slowness to act, lack of strength" .)