Ibuprofen target (4)
I believe the answer is:
ache
'ibuprofen target' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for ache that I've seen before include "Hurt; yearn" , "Dull throbbing pain" , "Long ? pain" , "Persistent dull pain" , "Nagging pain" .)