If car's faltering on ice, give up (9)
I believe the answer is:
sacrifice
'give up' is the definition.
(I know that sacrifice is a kind of give up)
'if car's faltering on ice' is the wordplay.
'faltering' indicates an anagram.
'on' says to put letters next to each other.
'cars' is an anagram of 'sacr'.
'if' put after 'sacr' is 'sacrif'.
'sacrif'+'ice'='SACRIFICE'
(Other definitions for sacrifice that I've seen before include "Immolate" , "Offering to a god" , "Give up" , "Destroy" , "Ritual killing" .)