If most indisposed by the head cold, get sweets (7)
I believe the answer is:
comfits
'sweets' is the definition.
(I know this)
'if most indisposed by the head cold' is the wordplay.
'indisposed' indicates anagramming the letters.
'by' means one lot of letters go next to another.
'the head' suggests taking the first letters.
The initial letter of 'cold' is 'c'.
'if'+'most'='ifmost'
'ifmost' anagrammed gives 'omfits'.
'omfits' after 'c' is 'COMFITS'.
'get' acts as a link.
I've seen this clue in the Evening Standard.
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