If upset, in dire need, make it clear! (6)
I believe the answer is:
define
'make it clear' is the definition.
I can't judge whether this defines the answer.
'if upset in dire need' is the wordplay.
'upset' indicates an anagram.
'in' means one lot of letters goes inside another.
'dire' is an anagram indicator.
'if' anagrammed gives 'fi'.
'need' is an anagram of 'dene'.
'fi' put within 'dene' is 'DEFINE'.
Can you help me to learn more?
(Other definitions for define that I've seen before include "Give precise meaning" , "Demarcate" , "Explain the meaning of a word" , "Give the meaning or mark the limits of" , "State the meaning of" .)