Ignoring the odds, tell couple to run off together (5)
I believe the answer is:
elope
'run off together' is the definition.
(I've seen this before)
'ignoring the odds tell couple' is the wordplay.
'ignoring the odds' means one should take alternating letters (letters in odd-numbered positions are removed).
'tell'+'couple'='tellcouple'
The alternate letters of 'tellcouple' are 'ELOPE'.
'to' is the link.
(Other definitions for elope that I've seen before include "Run away to Gretna Green?" , "Run away with one's beloved" , "run off with another?" , "(Lovers) run away" , "Run away with lover" .)