Illegal activity disturbing Central America (5)
I believe the answer is:
crime
'illegal activity' is the definition.
(I've seen this in another clue)
'disturbing central america' is the wordplay.
'disturbing' indicates anagramming the letters (I've seen this in other clues).
'central' indicates the central letters.
The centre of 'america' is 'meric'.
'meric' is an anagram of 'CRIME'.
(Other definitions for crime that I've seen before include "wrong-doing" , "Unlawful act" , "Offence punishable by law" , "Illegal deed" , "they say it doesn't pay" .)