Illegal activity disturbing Central America (5)
I believe the answer is:
crime
'illegal activity' is the definition.
(I've seen this before)
'disturbing central america' is the wordplay.
'disturbing' indicates an anagram (I've seen this in other clues).
'central' says to take the centre.
The middle letters of 'america' are 'meric'.
'meric' anagrammed gives 'CRIME'.
(Other definitions for crime that I've seen before include "wrong-doing" , "Unlawful act" , "Offence punishable by law" , "Illegal deed" , "they say it doesn't pay" .)