In a rush to charge queen (6)
I believe the answer is:
career
'in a rush' is the definition.
(career can mean to race around)
'charge queen' is the wordplay.
'charge' becomes 'care' (synonyms).
'queen' becomes 'ER' (abbreviation for Elizabeth Regina).
'care'+'er'='CAREER'
'to' acts as a link.
(Other definitions for career that I've seen before include "series of jobs" , "Not intellectual" , "Long-term occupation" , "Go at top speed through a working life?" , "Whole of employment" .)