In America, Jimmy Page is involved in Queen's comeback (5)
I believe the answer is:
prise
'in america jimmy' is the definition.
('jimmy' is a US term meaning 'prise')
'page is involved in queen's comeback' is the wordplay.
'page' becomes 'p'.
'involved in' is an insertion indicator.
'queen' becomes 'er' (abbreviation for Elizabeth Regina).
'comeback' shows that the letters should be reversed in order.
'er' written backwards gives 're'.
'is' placed inside 're' is 'rise'.
'p'+'rise'='PRISE'
(Other definitions for prise that I've seen before include "Lever open" , "Force open by leverage" , "Apply leverage" , "Spire (anag)" .)