Crossword Genius

In biology, a cavity or depression, such as any of the spaces in the matrix of bone (6)

Ross

I believe the answer is:

lacuna

(Other definitions for lacuna that I've seen before include "Space in book or manuscript" , "A gap, maybe in a book" , "Blank gap or missing part" , "Hiatus - cavity" , "A gap, or section missing from a book" .)

I've seen this clue in The Independent.
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