In charge in Italian city, woman ... (8)
I believe the answer is:
veronica
'woman' is the definition.
'in charge in italian city' is the wordplay.
'in charge' becomes 'ic'.
'in' means one lot of letters goes inside another.
'italian city' becomes 'verona' (I've seen this before).
'ic' put into 'verona' is 'VERONICA'.
(Other definitions for veronica that I've seen before include "Saint who wiped Christ's face on the Via Dolorosa" , "-- Lake, US film actress" , "Plant of the foxglove family in a cover, oddly" , "Plant also called speedwell -- I've no car (anag)" , "Plant with spikes of blue or purple" .)