In disagreement when going round to daughter and duke (2,4)
I believe the answer is:
at odds
'in disagreement' is the definition.
(thesaurus)
'when going round to daughter and duke' is the wordplay.
'when' becomes 'as'.
'going round' indicates putting letters inside.
'daughter' becomes 'd'.
'and' says to put letters next to each other.
'duke' becomes 'd'.
'to'+'d'+'d'='todd'
'as' enclosing 'todd' is 'AT ODDS'.
(Other definitions for at odds that I've seen before include "At variance (with)" , "In conflict with, oppposed to (2,4)" , "In disagreement or dispute" , "On bad terms" , "Not in agreement" .)