In Ephesus a new woman (5)
I believe the answer is:
susan
'woman' is the definition.
'in ephesus a new' is the wordplay.
'in' indicates the answer is hidden within the clue.
'SUSAN' is hidden within 'ephesus a new'.
(Other definitions for susan that I've seen before include "When lazy, she's a revolving tray on a dining table" , "Girl's name; lazy -" , "- - Sarandon (films)" , "Girl's name, meaning lily" , "-- Howatch, novelist" .)