In general, worried about regularly overlooked German student being upset (2,5)
I believe the answer is:
at large
'in general' is the definition.
(synonyms)
'worried about regularly overlooked german student being upset' is the wordplay.
'worried' becomes 'ate' (something worrying may eat someone up).
'about' means one lot of letters goes inside another.
'regularly overlooked' means one should take alternating letters (letters removed at regular intervals).
'student' becomes 'l' (as in L-plates for learner drivers).
'being upset' says the letters should be written backwards.
The alternating letters of 'german' are 'gra'.
'gra'+'l'='gral'
'gral' in reverse letter order is 'larg'.
'ate' going around 'larg' is 'AT-LARGE'.
(Other definitions for at large that I've seen before include "Escaped, not captured" , "Free - in general" , "On the loose, at liberty" , "Glare at, being free and not confined" , "Free to roam about, not in confinement" .)