In general worried about US city risking being evacuated (2,5)
I believe the answer is:
at large
'in general' is the definition.
(synonyms)
'worried about us city risking being evacuated' is the wordplay.
'worried' becomes 'ate' (something worrying may eat someone up).
'about' indicates putting letters inside.
'us city' becomes 'LA' (Los Angeles).
'being evacuated' says to hollow out the word (remove centre letters) (internal letters are evacuated from the word).
'risking' with its middle removed is 'rg'.
'la'+'rg'='larg'
'ate' enclosing 'larg' is 'AT-LARGE'.
(Other definitions for at large that I've seen before include "Free to roam about, not confined" , "Glare at, being free and not confined" , "a wild animal may roam so" , "On the run" , "Escaped, not captured" .)