In-laws call regularly about Hooters (5)
I believe the answer is:
nasal
'about hooters' is the definition.
('hooter' can mean the nose)
'in-laws call regularly' is the wordplay.
'regularly' indicates alternate letters (regularly take one letter, leave next etc.).
'in'+'laws'+'call'='inlawscall'
The alternate letters of 'inlawscall' are 'NASAL'.
(Other definitions for nasal that I've seen before include "piece of armour" , "Like a twang" , "Part of helmet" , "Relating to a facial organ" , "Of sound, as if it came through the nose" .)