In-laws ought to heartily chuckle (5)
I believe the answer is:
laugh
'chuckle' is the definition.
(I've seen this before)
'in-laws ought to heartily' is the wordplay.
'in laws' becomes 'la' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'to heartily' indicates the central letters (the inside or heart of the word).
The centre of 'ought' is 'ugh'.
'la'+'ugh'='LAUGH'
Can you help me to learn more?
(Other definitions for laugh that I've seen before include "Break up" , "Show mirth" , "Sound amused" , "Express joy or amusement" , "Good fun" .)