In no end of bother, compiler is in a rage (5)
I believe the answer is:
fumes
'is in a rage' is the definition.
(to fume is to be very angry)
'in no end of bother compiler' is the wordplay.
'in' indicates putting letters inside.
'no end of' means to remove the last letter.
'bother' becomes 'fuss' (synonyms).
'compiler' becomes 'me' (the person who is writing these clues).
'fuss' with its final letter taken away is 'fus'.
'fus' placed around 'me' is 'FUMES'.
(Other definitions for fumes that I've seen before include "Clouds of smelly vapour" , "Smokes; rages" , "Unpleasant vapour" , "Seethes with anger, smokes (5)" , "Smoulders or smokes" .)