In no time, a local concocted soothing medicine (8,6)

I believe the answer is:

calamine lotion

'soothing medicine' is the definition.
(calamine lotion is a type of medicine)

'in no time a local concocted' is the wordplay.
'concocted' indicates anagramming the letters.
'in'+'no'+'time'+'a'+'local'='innotimealocal'
'innotimealocal' with letters rearranged gives 'CALAMINE LOTION'.

(Other definitions for calamine lotion that I've seen before include "calmer" , "soothing stuff" .)

I've seen this clue in The Guardian.

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