In practice, Rod came round and wakened one up (3)
I believe the answer is:
use
'in practice' is the definition.
'use' can be an answer for 'practice' (use is a kind of practice). I'm unsure of the 'in' bit.
I cannot understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for use that I've seen before include "consume; exploit" , "Employment; utilise" , "Take drugs regularly" , "Put into service, do something with" , "Put to a particular purpose" .)