In reality, after a fat mascot collapsed? (2,1,6,2,4)
I believe the answer is:
as a matter of fact
'in reality' is the definition.
(I've seen this before)
'after a fat mascot collapsed?' is the wordplay.
'collapsed?' is an anagram indicator.
'after'+'a'+'fat'+'mascot'='afterafatmascot'
'afterafatmascot' anagrammed gives 'AS A MATTER OF FACT'.
(Other definitions for as a matter of fact that I've seen before include "in reality" , "Actually" .)