... in Rome: sex and food? (5)
I believe the answer is:
viand
'food?' is the definition.
(archaic term for food)
'in rome sex and' is the wordplay.
'in rome sex' becomes 'vi' (I am not sure about this - if you are sure you should believe this answer much more).
'vi'+'and'='VIAND'
Can you help me to learn more?
(Other definitions for viand that I've seen before include "Item of food (arch.)" , "something to eat" , "Meat; article of food" , "loaf of bread, maybe?" .)