In Serengeti, grisly river! (6)
I believe the answer is:
tigris
'river' is the definition.
(Tigris River is an example)
'in serengeti grisly' is the wordplay.
'in' indicates the answer is hidden within the clue.
'TIGRIS' can be found hidden inside 'serengeti grisly'.
(Other definitions for tigris that I've seen before include "Sit rig into the Asian river" , "It flows through Iraq" , "Tributary of the Euphrates River" , "Euphrates companion river" , "River of Turkey/Iraq" .)