In the end, you miss the service (3)
I believe the answer is:
use
'service' is the definition.
(to be of service is to be of use)
'in the end you miss the' is the wordplay.
'in the end' says to take the final letters.
The final letters of 'you miss the' are 'USE'.
(Other definitions for use that I've seen before include "Value" , "Custom - service" , "Employ (something)" , "Practise" , "Exploit; custom" .)