In the least degree a giant! (2,3)

I believe the answer is:

at all

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'in the least' is the definition.
('at all' can be a synonym of 'in the least')

I can't explain the rest of the clue.

(Other definitions for at all that I've seen before include "Whatsoever" , "in any way" , "in any circumstances" .)

I've seen this clue in the Evening Standard.

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