In very different ways, a solitary individual (5)
I believe the answer is:
loner
'solitary individual' is the definition.
(I've seen this before)
'in very different ways a' is the wordplay.
'in' means one lot of letters goes inside another.
'very different ways' becomes 'lr' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'a' becomes 'one'.
'lr' placed around 'one' is 'LONER'.
Can you help me to learn more?
(Other definitions for loner that I've seen before include "Unsociable person" , "Antisocial person" , "Person who prefers his own company" , "One who avoids company" , "One preferring to act individually" .)