In Virginia, U.S., a little town that's different (7)
I believe the answer is:
various
'different' is the definition.
(similar in meaning)
'in virginia u s a little town' is the wordplay.
'in' means one lot of letters goes inside another.
'virginia' becomes 'va' (US state abbreviation).
'a little town' becomes 'rio' (I am not sure about this - if you are sure you should believe this answer much more).
'va'+'u'+'s'='vaus'
'vaus' going around 'rio' is 'VARIOUS'.
'that's' acts as a link.
Can you help me to learn more?
(Other definitions for various that I've seen before include "Saviour of many kinds" , "Of several different kinds" , "Of many different kinds" , "Sundry" , "Manifold" .)