Individual, interrupting vacuous gangster, is doomed (5)
I believe the answer is:
goner
'is doomed' is the definition.
I can't judge whether this defines the answer.
'individual interrupting vacuous gangster' is the wordplay.
'individual' becomes 'one' (an individual is one person).
'interrupting' is an insertion indicator.
'vacuous' says to hollow out the word (remove centre letters).
'gangster' with its centre taken out is 'gr'.
'one' put inside 'gr' is 'GONER'.
Can you help me to learn more?
(Other definitions for goner that I've seen before include "who's asleep" , "A has-been in distress" , "I'm late" , "one with no life left" , "Lost cause" .)