Inhospitable house with broken tiles (7)
I believe the answer is:
hostile
'inhospitable' is the definition.
(synonyms)
'house with broken tiles' is the wordplay.
'house' becomes 'ho' (abbreviation for house).
'with' is a charade indicator (letters next to each other).
'broken' indicates an anagram.
'tiles' with letters rearranged gives 'stile'.
'ho'+'stile'='HOSTILE'
(Other definitions for hostile that I've seen before include "Enemy" , "malevolent" , "harsh" , "Aggressive" , "Antagonistic" .)