Initiation in diabolism? Issue making you resign! (5)
I believe the answer is:
demit
'resign' is the definition.
(demit means to resign from a post)
'initiation in diabolism? issue' is the wordplay.
'initiation in diabolism?' becomes 'd' (I can't justify this - if you can you should believe this answer much more).
'issue' becomes 'emit' (both can mean to give out or radiate).
'd'+'emit'='DEMIT'
'making you' is the link.
Can you help me to learn more?
(Other definitions for demit that I've seen before include "Send" , "Timed (anag.); to lower or to resign" , "Yield" , "Dismiss" .)