Crossword Genius

Injurious commercial, very Irish (7)

Ross

I believe the answer is:

adverse

'injurious' is the definition.
(thesaurus)

'commercial very irish' is the wordplay.
'commercial' becomes 'ad'.
'very' becomes 'v' (abbreviation).
'irish' becomes 'erse' (I've seen this before).
'ad'+'v'+'erse'='ADVERSE'

(Other definitions for adverse that I've seen before include "In an opposing direction" , "Conflicting" , "Inimical" , "negative result" , "Opposed to or unfavourable" .)

I've seen this clue in The Times.
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