Insecure lady shunning outside with separation (6)
I believe the answer is:
adrift
'insecure lady shunning outside with separation' is the definition.
I can't judge whether this defines the answer.
'outside with separation' is the wordplay.
'outside' suggests removing the centre (I've seen 'outside of' mean this).
'with' becomes 'and' (I've seen this before).
'separation' becomes 'rift' (I am not sure about this - if you are sure you should believe this answer much more).
'and' with its middle removed is 'ad'.
'ad'+'rift'='ADRIFT'
Can you help me to learn more?
(Other definitions for adrift that I've seen before include "Unanchored - lost" , "(Of boat) moving out of control" , "'Directionless, floating freely (6)'" , "(Of ship) out of control" , "Unsettled or unanchored" .)