Insignificant person making the solving of the murder very difficult! (6)
I believe the answer is:
nobody
'insignificant person' is the definition.
(I've seen this before)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for nobody that I've seen before include "Eg Pooter" , "Not one person" , "who can square the circle?" , "The Diary of a - - (G & W Grossmith)" , "Insignificant person" .)