Instrument played by Difford and Tilbrook's band on TV (7,3)
I believe the answer is:
squeeze box
'instrument played' is the definition.
(musical instrument)
'difford and tilbrook's band on tv' is the wordplay.
'difford and tilbrook's band' becomes 'Squeeze' (band featuring Glenn Tilbrook and Chris Difford).
'on' is a charade indicator (letters next to each other).
'tv' becomes 'box'.
'squeeze'+'box'='SQUEEZE-BOX'
'by' acts as a link.
(Other definitions for squeeze box that I've seen before include "Concertina" , "musical instrument" , "Music-maker" , "Accordion" , "producer of note" .)