Interference in this sense (4)
I believe the answer is:
hiss
'interference' is the definition.
(I've seen this before)
'in this sense' is the wordplay.
'in' says the answer is hidden in the clue.
'HISS' is hidden within 'this sense'.
(Other definitions for hiss that I've seen before include "Boo" , "Wordless sound of disapproval" , "Make snake-like noise" , "Audio interference" , "Sound of serpent" .)