Intertwine most of garland (6)
I believe the answer is:
wreath
'garland' is the definition.
(I know that garland can be written as wreath)
'intertwine most' is the wordplay.
'intertwine' becomes 'wreathe' (wreathing is a kind of intertwining).
'most' means to remove the last letter.
'wreathe' with its final letter taken off is 'WREATH'.
'of' is the link.
(Other definitions for wreath that I've seen before include "Circular garland" , "The war (anag.)" , "Circle of flowers for mourning" , "Funeral arrangement" , "Circle of flowers or foliage" .)