Invigorating substance (5)
I believe the answer is:
tonic
(Other definitions for tonic that I've seen before include "something medicinal" , "requirement for invigoration?" , "Key" , "__water; gin mixer" , "that may be mixed with gin" .)
I believe the answer is:
tonic
(Other definitions for tonic that I've seen before include "something medicinal" , "requirement for invigoration?" , "Key" , "__water; gin mixer" , "that may be mixed with gin" .)