Involve directions to follow (6)
I believe the answer is:
entail
'involve' is the definition.
(entail means to involve or require)
'directions to follow' is the wordplay.
'directions' becomes 'en' (east and north).
'to follow' becomes 'tail' (both can mean to chase or pursue).
'en'+'tail'='ENTAIL'
(Other definitions for entail that I've seen before include "Inalienable estate" , "Involve or make necessary" , "settlement of estate" , "Inevitably result in" , "outmoded fashion" .)