Iris and Pat at odds about right runway (8)
I believe the answer is:
airstrip
'runway' is the definition.
(thesaurus)
'iris and pat at odds about right' is the wordplay.
'and' is a charade indicator (letters next to each other) (I've seen this in other clues).
'at odds' indicates anagramming the letters.
'about' means one lot of letters goes inside another.
'right' becomes 'r' (common abbreviation).
'iris' after 'pat' is 'patiris'.
'patiris' is an anagram of 'aistrip'.
'aistrip' going around 'r' is 'AIRSTRIP'.
(Other definitions for airstrip that I've seen before include "for those taking flight?" , "Rough landing area" , "Small runway" , "From which you might take off" , "(Unprepared) runway" .)