Irksome person (4)
I believe the answer is:
pest
'irksome person' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for pest that I've seen before include "Nuisance; half a European capital" , "Destructive insect or other animal" , "Annoying person" , "Destructive creature" , "Annoying creature" .)