Irritable cats cry, running wild around hospital (8)
I believe the answer is:
scratchy
'irritable' is the definition.
(I've seen this before)
'cats cry running wild around hospital' is the wordplay.
'running wild' indicates anagramming the letters.
'around' indicates putting letters inside.
'hospital' becomes 'h'.
'cats'+'cry'='catscry'
'catscry' is an anagram of 'scratcy'.
'scratcy' enclosing 'h' is 'SCRATCHY'.
(Other definitions for scratchy that I've seen before include "Like many an old record" , "carelessly" , "bad-tempered" , "after scoring" , "Playing badly" .)